The minutes of a press conference in Beijng from February where Chinese medical experts on the front line outline to the government what worked for them when treating covid-19 patients
Moderator: Mi Feng , Spokesperson of the National Health and Health Commission, Deputy Director of the Department of Publicity
Guest: Guo Yanhong Supervisor, Medical Administration and Hospital Administration, National Health and Health Commission
Jiang Jian Director, Department of Medical Affairs, State Administration of Traditional Chinese Medicine
Li Yu Director of Science and Technology Department of the State Administration of Traditional Chinese Medicine
Sun Yanrong Deputy Director, Biological Center, Ministry of Science and Technology
Guiqiang Wang Chief Physician, Peking University First Hospital
Good afternoon, media friends! I am Mi Feng, spokesperson of the National Health and Health Commission and deputy director of the Propaganda Department. Welcome to the press conference of the State Council's Joint Prevention and Control Mechanism. The treatment of patients with new crown pneumonia has always affected everyone's hearts. The majority of medical workers and scientific and technical workers are working hard to prevent the virus and cure patients, and they are working hard to improve the cure rate and reduce the mortality rate. Today's conference theme is: medical treatment progress and cure.
We invited Ms. Guo Yanhong, Supervisor, Medical Administration and Hospital Administration, National Health and Health Commission, Ms. Jiang Jian, Director of the Department of Medical Affairs, State Administration of Traditional Chinese Medicine, Mr. Li Yu, Director of the Science and Technology Department, Ms. Sun Yanrong, Deputy Director of the Biological Center of the Ministry of Science and Technology, and Peking University The chief physician of the hospital, Mr. Wang Guiqiang, asked them to answer media questions and introduce health knowledge about improving the efficiency of detection and treatment, the progress of clinical drug trials, and caring for medical staff.
First, let us know the situation.
2 Yue 16 Ri 0 when - 24- time, the provinces (autonomous regions and municipalities) and Xinjiang Production and Construction Corps new confirmed cases reported 2048 cases of new deaths in 105 cases, including Hubei, 100 cases of Henan 3 cases, Guangdong 2 cases. 1563 suspected cases were added . On the same day, 1,425 cases were cured and discharged , 28,179 close contacts were released from medical observation , and 628 severe cases were reduced .
As of 2 Yue 16 Ri 24 when, according to the provinces (autonomous regions and municipalities) and Xinjiang Production and Construction Corps report, existing confirmed cases 57934 cases, including severe cases 10644 cases. Cumulative cases were cured 10844 cases of cumulative cases of death 1770 cases of confirmed cases reported a total of 70548 cases of suspected cases existing 7264 cases. Cumulative traced to close contact with 546016 people, is still under medical observation in close contact with 150,539 people.
There were 1933 newly confirmed cases in Hubei Province , of which 1690 were in Wuhan ; 1016 new cases were cured and discharged , of which 543 were in Wuhan ; 100 new deaths were reported , of which 76 were in Wuhan ; 49847 confirmed cases were currently in Wuhan, of which 36385 were in Wuhan ; There were 9,977 severe cases , including 8056 in Wuhan . Cumulative cases were cured 6639 cases, of which Wuhan 3458 cases; cases of cumulative death 1696 cases, of which Wuhan 1309 cases; confirmed cases total of 58182 cases, including Wuhan 41152 cases. There were 909 new suspected cases , including 338 in Wuhan ; 4826 suspected cases , including 1971 in Wuhan .
A total of 87 confirmed cases were reported from Hong Kong, Macao and Taiwan , including 57 from the Hong Kong Special Administrative Region ; 10 from the Macao Special Administrative Region ; and 20 from Taiwan .
With the exception of Hubei, there were 115 new confirmed cases , 654 new suspected cases , 5 new deaths , and 29 severe cases reduced . The total number of newly confirmed cases has declined for 13 consecutive days, and the number of new deaths has remained low.
The above is the epidemic situation. 2020-02-17 15:01:31
Now I will inform a situation, 2 Yue 16 evening, the National Committee to organize a new health epidemic prevention and control of pneumonia crown forum in Beijing. About 80 representatives from the China-WHO Joint Experts Team on New Crown Pneumonia and relevant member units of the State Council Joint Prevention and Control Mechanism attended the meeting.
Deputy Director Li Bin of the National Health and Health Commission introduced the situation of the national epidemic prevention and control, saying that the prevention and control work had achieved positive results, and the situation of the epidemic situation had changed positively. China will continue to work with the international community to jointly address the challenges of the epidemic and safeguard global health and safety. The joint inspection team is welcome to make suggestions on China and the global epidemic prevention and control.
Representatives from the Ministry of Science and Technology, the Ministry of Agriculture and Rural Affairs, the General Administration of Customs, the Forestry and Grass Bureau, the Drug Administration, and the Chinese Medicine Bureau introduced the prevention and control work in their respective fields. The responsible comrades of the Hubei Provincial Government introduced the local epidemic prevention and control situation through a video link, and provincial and municipal health and health administrative departments and professionals participated in the exchange.
The inspection team and participants fully exchanged information on the epidemic situation, community and rural prevention and control, wildlife management, development of drugs and vaccines, etc., praised China's comprehensive prevention and control measures and achieved results, and praised China's medical services Admiration of the staff's selflessness.
Joint study group of experts will be held 2 Yue 17 Ri went to Beijing, Guangdong and Sichuan provinces to carry out site visits. The above is the situation of notification.
Let ’s move on to today ’s on-site questioning session. Please inform your news organization before asking a question. 2020-02-17 15:09:25
CCTV reporter :
According to media reports, there have been more than 20,000 medical workers across the country. Which departments do these medical staff come from? Medical treatment staff in Wuhan need to cooperate with each other for medical treatment. How to complete the running-in work and improve the treatment efficiency? Thank you. 2020-02-17 15:10:02
Please ask Ms. Guo Yanhong to answer this question. 2020-02-17 15:14:07
Guo Yanhong :
Thank you for your question. Doing everything possible to treat patients is the top priority in the current epidemic prevention and control work, especially for Wuhan, Hubei, where there are many patients, severe illnesses, and treatment tasks are very important. Therefore, we use national efforts to support Wuhan and Hubei to complete the treatment of patients. Work to increase the rate of treatment and cure, reduce mortality and infection. Wuhan support from the national rush to the rescue efforts of view, now 29 provinces (autonomous regions and municipalities) including Xinjiang Production and Construction Corps and the military system has sent 3 million to support medical staff in Wuhan, Hubei, mainly from respiratory infection, such as severe Professional and a large team of nursing staff. In view of the characteristics of many serious illnesses in Wuhan, we have the strongest professional medical care force, with 11,000 serious professional medical staff responsible for the treatment of severe illnesses. These 11,000 critical medical staff are close to 10% of the national critical medical staff resources , but we will still assist Wuhan and Hubei to resolutely complete the rescue work and safeguard the health of the people. In addition, we call out the elite army, which is the highest level of medical care. There are three academician teams, Academician Zhong Nanshan, Academician Li Lanjuan, and Academician Wang Chen. They have been working in the front line, making suggestions in the treatment of complex critical illnesses, especially exploring Some new treatment methods and technologies have been introduced, and these effective treatment methods and technologies have been incorporated into the treatment plan. At present, we are forming the sixth edition of the diagnosis and treatment plan to guide the nationwide treatment and improve the level of treatment.
In addition, it has mobilized 22 national emergency medical rescue teams across the country, equipped with sophisticated equipment, which can help Wuhan improve the level of treatment. In addition, there are three P3 mobile laboratories and testing personnel to help Wuhan and Hubei improve their testing capabilities, testing results, and speed of diagnosis. In addition to Wuhan, there are 16 prefectures and cities. For the 16 prefectures and cities, we adopt the model of "provincially contracting cities". By focusing on the provinces, cities, responsibilities, tasks, and implementation details, we focus on "two improvements, two declines. . For 16 cities in more serious epidemic Methods provinces and one city of Huanggang package, Xiaogan, Jingzhou, Hubei Province held a national effort to help, to help accomplish the appropriate treatment Wuhan task. Thank you. 2020-02-17 15:15:26
Economic Daily News reporter :
There are many rumors about new crown pneumonia, and some people think that the fight against new crown pneumonia virus relies on autoimmunity. I would like to ask if there is a clear diagnosis and treatment method for new coronary pneumonia, can it be cured? Will it recur after cure? 2020-02-17 15:22:04
Guo Yanhong :
Our answer is clear. Although this disease is a new infectious disease, it is preventable and treatable. As of 2 Yue 16 to the latest data of the day, cured patients greater than one million and also pleased to see that in addition to the national situation of Hubei, the confirmed number of cases has been achieved consecutive 13 -day decline, which is a very good sign that we The prevention and control work has achieved very good results. By analyzing the situation of the discharged patients, it should be said that some effective diagnosis and treatment strategies and methods have been formed for the cured patients. About 90% of these discharged patients are mild and about 10% are severe and critically ill. By subdivision, the period from the onset of the patient to the diagnosis, the national average is 4.95 days, indicating that we shorten the diagnosis time, timely diagnosis and treatment, early diagnosis and early treatment, is also a very effective measure to improve the cure rate. We have also analyzed the treatment of all patients. More than 90% of patients have adopted a comprehensive series of diagnostic and therapeutic methods such as antiviral therapy and symptomatic treatment, including respiratory support, circulatory support, and immunity enhancement to accelerate patients. Of cure. In addition, we are glad to see that the situation in Wuhan has also changed a lot. Especially recently, through early diagnosis and early treatment, and through continuous observation after treatment of mild patients, we can see that the proportion of severe cases has dropped from 38% at the beginning to 18% at present . Therefore, it should be said that "four early" and "four concentration" are very effective measures to improve the cure rate, the admission rate, and reduce the infection rate and mortality. These measures combined with the effective treatment methods in the clinic, I believe we will sum up a series of experiences and methods to improve the treatment capacity and improve the cure rate. Not only for our domestic use to strengthen the treatment work, but also to provide useful and valuable experience internationally. 2020-02-17 15:27:31
CCTV reporter :
You also mentioned that you are continuously increasing the strength of counterpart medical support. What specific measures are there to alleviate the difficulties of front-line medical staff with heavy work tasks, high risk of infection, and high psychological pressure? What specific arrangements are there for front-line medical staff rotation? 2020-02-17 15:27:57
Guo Yanhong :
First of all, everyone must be proud and proud of the medical staff of the motherland. They have practiced the noble spirit of worshiping life, saving lives, helping, and devotion. They are the loveliest people in the new era. They are Chinese. Heroes are also heroes of the world. Therefore, protecting the physical and mental health of medical personnel is an important guarantee for them to complete their medical treatment. Not long ago, the General Office of the State Council reposted "Several Measures on Improving the Working Conditions of Frontline Medical Staff and Practically Caring for the Physical and Mental Health of Medical Staff" by the National Health and Health Commission, the Ministry of Human Resources and Social Security, and the Ministry of Finance, and provided our medical staff from various aspects Better protection. The "Notice" requires "to create a good environment conducive to the work of medical staff, to rationally arrange the work and rest time of medical staff, to strengthen the personal protection of medical staff, to carry out targeted intervention and psychological counseling, and to strengthen the medical staff Humanistic care and good logistical services for our medical staff. "It should be said that through multiple measures, we truly serve medical staff and provide them with the greatest guarantee for their undivided involvement in patient care. At present, the medical staffs ahead are indeed carrying very heavy work tasks, and they are not only working hard and having a high risk of infection, they are also very stressed. Therefore, we have detailed the work measures, detailed the work arrangements of medical staff, and scheduled shifts. We hope that front-line medical staff can not only complete the treatment of patients, but also maintain themselves to the maximum extent possible. Physical and mental health. Thank you. 2020-02-17 15:31:59
Phoenix TV reporter :
A question about drug research. Earlier concerned that the relevant person in charge of the Ministry of Science and Technology introduced at the press conference that three drugs are being tested in clinical trials, namely chloroquine phosphate, fapilavir, and ridicvir. Are there any drugs that have shown clear results? In addition, are there any prescriptions that have been proven effective in Chinese medicine? 2020-02-17 15:32:18
Please ask Ms. Sun Yanrong to answer first. 2020-02-17 15:34:26
Sun Yanrong :
In the face of the rapid development of this epidemic, how to improve the cure rate has always been the most important task in scientific research. The drug research and development work has always been carried out in accordance with the new thinking of old drugs. The scientific research group organized national scientific and technological forces and screened from layer to layer, from tens of thousands of drugs to thousands, to hundreds, to tens, to several, so a veritable old drug such as chloroquine phosphate appeared before us, also for We bring new hope. The so-called "old", this drug is an antimalarial drug, which has been introduced before and has been used clinically for more than 70 years. Previous research has clearly indicated that it has not only antimalarial effects but also broad-spectrum antiviral effects. In addition, there are immune regulation effects. Based on this, in the face of this new virus, a new epidemic, and a new disease, it is not only necessary to look at the in vitro action of the drug, but also to conduct an effective clinical evaluation to determine whether the drug is really acceptable. There are new uses. We organized more than a dozen hospitals in Beijing, Guangdong and Hunan provinces to jointly evaluate the safety and effectiveness of chloroquine phosphate in the treatment of new coronary pneumonia. In the clinic, we are very sure to see the curative effect, whether it is from the rate of exacerbation, antipyretic phenomenon or the image improvement time of the lungs, the negative time and negative rate of viral nucleic acid, and the shortening of the disease course, and a series of indicators, systematically Based on comprehensive research, the medication group was better than the control group. For example, a patient in Beijing was admitted to the hospital on the 4th day of the onset of disease at the age of 54. One week after taking the medicine, the nucleic acid turned negative, and all the indicators improved, meeting the criteria for release and isolation.
In addition, we are extremely concerned about drug safety. So far, there have been no drug-related, serious serious adverse reactions in more than 100 patients. Based on the above findings, 2 Yue 15 days in Beijing jointly organized by the Ministry of Science and key members of the unit, health committee, the Food and Drug Administration and other scientific research group held a video specialists, team leader of the meeting was Dr. Nanshan Zhong served as academician, and several drug development and clinical experts participated in the expert demonstration to jointly study the efficacy of chloroquine phosphate on new coronary pneumonia. The expert group reached a consensus after careful and meticulous research and concluded that "the drug is an old drug that has been on the market for many years, and its safety for the treatment of a wide range of people is controllable. Based on the results of research conducted by previous clinical institutions, it can be clarified Chloroquine phosphate has a certain effect in the treatment of new coronary pneumonia. "Based on the urgent needs of clinical treatment, experts unanimously recommend that" chloroquine phosphate should be included in the new edition of the diagnosis and treatment guidelines as soon as possible, and the scope of clinical trials should be expanded. " Therefore, we look forward to the idea of using old medicines and new medicines, so that the 70- year old medicines can play a newer and better role in fighting the epidemic as soon as possible .
At the same time, I would also like to introduce one point. During the scientific research to combat the epidemic, the scientific research team attached great importance to the role of Chinese medicine. We will work with the Chinese Medicine Bureau to actively and systematically arrange scientific research related to Chinese medicine in emergency projects. The scientific research work led by Academician Zhang Boli and Academician Huang Luqi is progressing in an orderly manner and has achieved certain results. We also hope to hear from Director Li Yu. 2020-02-17 15:36:45
Li Yu :
After the epidemic, under the overall arrangement of the scientific research team of the Joint Prevention and Control Mechanism of the State Council, our bureau quickly launched two emergency special projects: "Chinese Medicine Prevention and Treatment of 2019- New Crown Virus" and "Clinical Research of Integrated Traditional Chinese and Western Medicine on New Crown Pneumonia" These two special projects were led by Academician Huang Luqi and Academician Zhang Boli, and carried out related clinical research work in Wuhan Jinyintan Hospital, Beijing Ditan Hospital, and Hubei Province Integrated Traditional Chinese and Western Medicine Hospital. China Academy of Chinese Medical Sciences, Tianjin University of Traditional Chinese Medicine and other units have successively carried out clinical research work on screening of traditional Chinese medicines, and the project progress has been progressing smoothly.
At the same time, the Bureau clinical "emergencies, practical utility" as a guide for 1 Yue 27 Ri launched the "New clinical screening crown pneumonia prevention and treatment of traditional Chinese medicine prescription effective" work. Clinical observation and data analysis were performed on the clinical efficacy of the traditional Chinese medicine compound "Qingfei Paidu Decoction" in Shanxi, Hebei, Heilongjiang, and Shaanxi in the treatment of neo-pneumocoronary pneumonia. In obtaining 214 case of clinical cases of valid data, 2 Yue 6 from country Wei Jian Commission, the State Administration of Traditional Chinese Medicine jointly issued a document to the nation recommended clearing the lungs detoxification soup. At present, 701 confirmed cases of Qingfei Paidu Decoction in 57 designated medical institutions in 10 provinces have been included for observation. Among them, 130 were cured and discharged, 51 had disappeared symptoms, 268 had improved symptoms, and 212 had stable symptoms without exacerbation. Analysis and statistics of 351 cases with detailed case information . Before taking Qingfei Detox Decoction, 112 cases had a body temperature exceeding 37.3 ° C, and 51.8% of the patients returned to normal temperature after taking the medicine for one day ; 94.6% of patients had taken the body temperature after taking the medicine for six days Return to normal; 214 patients with cough symptoms, taking medication 1After 6 days, cough symptoms disappeared in 46.7% of patients; in 60.8 days, cough symptoms disappeared in 80.6% of patients. At the same time, it also has obvious effects on other symptoms, such as fatigue, poor appetite, and sore throat. Of these 351 patients, none of the light and ordinary patients were converted to severe or critically ill; 3 of the 22 severely ill patients were cured and discharged, and 8 were converted to the general type; a total of 46 were cured and discharged. The above data also show that Qingfei Paidu Decoction has good clinical efficacy and treatment prospects for the treatment of new coronary pneumonia, which has also increased our confidence and determination to overcome the epidemic.
While carrying out treatment, various regions have also actively carried out related clinical research work, and introduced some effective prescriptions and prescriptions. For example, the "Pneumonia No. 1" launched by Guangzhou Eighth Hospital has also achieved good clinical results. 2020-02-17 15:40:04
Reporter of Hunan Radio and Television News Center :
According to recent media reports, some experts have stated that the quality of nucleic acid reagents is not stable at present, with a positive detection rate of 30% to 50% . Commissioner Guo also said earlier that early diagnosis and early treatment are needed. In the face of this situation, how to strengthen clinical diagnosis, there are No other test can help confirm the diagnosis? For example, what we call lung CT and blood routine. Thank you. 2020-02-17 15:42:59
Wang Guiqiang :
Thank you for this reporter's question. First of all, the stability of the nucleic acid test itself is very good. There are some so-called undetectable cases or false negatives. The main reason is that any detection method has a sensitivity problem. From the aspect of the disease, it may be that the amount of virus is very small, and it may not be detected in the upper respiratory tract. Of course, there are problems with sampling methods, such as the emphasis on throat swabs. The positive rate of diagnosis will increase substantially. Nucleic acid testing is currently the "gold standard" for the diagnosis of new coronary pneumonia. Only a positive nucleic acid test can confirm the diagnosis. The health and health committee is also working on joint efforts to improve the sensitivity and specificity of the test.
Just now you mentioned that our diagnosis of new coronary pneumonia infection is very important in combination with clinical and imaging diagnosis. We propose the concept of clinical diagnosis. Through clinical manifestations, the management and treatment of this disease can be started without pathogens. Through clinical diagnosis, patients can be isolated and treated in time to improve the cure rate, reduce the mortality rate, and avoid further transmission. Now, we have strengthened our comprehensive diagnostic capabilities in clinical practice.
In another aspect, some researches are still being done, such as antigen detection and antibody detection. Now the Ministry of Science and Technology has also launched research projects to use antigen and antibody detection for clinical patients. It is believed that the use of these new methods will further improve the diagnosis of new coronary pneumonia. Specificity and sensitivity make patients more effective and timely diagnosis and treatment. Thank you. 2020-02-17 15:47:03
Xinhua News Agency :
One problem specific plasma treatment, in 2 Yue 13 when the number of Chinese bio said it had recovered plasma with clinical treatment of critically ill patients, the treatment effect is remarkable. Would you like to ask, what is the principle of plasma treatment in the recovery period? What kind of people can donate specific plasma? What are the expectations for the current treatment? 2020-02-17 15:47:26
Sun Yanrong :
There are still more than 10,000 severely ill patients that affect everyone's heart. Scientific research work also treats the treatment of critically ill patients as a top priority, and clinically urgently requires effective treatment methods to reduce the mortality of critically ill patients. Recovery plasma therapy is one of the oldest and innovative first aid measures, and has been applied to sudden infectious diseases in the past ten years. Scientific research group at 1 Yue 22 of the first research project day emergency contingency set up, the recovery period will be incorporated into the plasma preparation work to support the project, the technology research progress made in a press conference has been made Brief introduction. We are concerned that everyone is very concerned about this research work. As the information you know, China is our biological emergency special commitment unit, after the Chinese bio-technology projects undertaken emergency, emergency start deployed in Wuhan, 2 Yue 1 collection date to the first plasma in patients with convalescent, 2 Yue 9 days The first severely ill patient received treatment at Wuhan First People's Hospital, and 10 patients received treatment in the following week . As far as we know, 1 of the patients being treated has already been discharged from hospital and 1 has been able to walk down the ground. The remaining several patients are in recovery period. We will also pay close attention to clinical progress. The scientific research team will also perform the expected curative effect and risk assessment on the plasma treatment methods in the recovery period, and we will follow up and judge in time.
At present, for severe treatment, clinical studies have shown that the plasma in the recovery period is safe and effective. This is a systematic project that affects the whole society. It requires the cooperation of the government, hospitals, enterprises, medical staff, and rehabilitators in a short time. Within the maximum effect of treating critically ill patients. The Ministry of Science and Technology will also cooperate with the Health and Medical Commission to promote this work to be widely used in clinical practice. Here, I would like to take this opportunity to sincerely thank the first lady who donated 300 ml of plasma. We sincerely thank all the patients who donated plasma, because their dedication provided a powerful weapon for the clinical treatment of critically ill patients. Because of their efforts, they bring new hope to the critically ill patients who are struggling on the lifeline. Currently, cure the patient has more than 1 million, but we have to remember that critically ill patients are still 1 million bits, and cure of patients with 1 million of their hopes. Here, we call for the "Thousands of People to Save Thousands of People" campaign in the whole society. We hope that more rehabilitation people can extend their arms and donate blood plasma, so that love can be relayed and life can be continued. As long as the whole society works together , Will certainly overcome the epidemic. 2020-02-17 15:50:27
Guo Yanhong :
Recovery plasma therapy is a very effective and important method for severe and critically ill patients. In the fifth edition of the diagnosis and treatment plan, the treatment method of the recovered patients' plasma has been included. In the sixth edition plan to be revised, we will also refine the relevant content. In fact, the plasma treatment of the recovering patients is actually using a certain titer of virus-specific antibodies in the plasma of the recovering patients to reduce the virus content in the patients, thereby achieving the treatment expectations. At present, the clinical treatment of existing cases has shown good results. For recovery period plasma, there are strict quality control requirements from its collection, preparation, storage, and clinical application. At the same time, we guide the establishment of provincial-level expert groups throughout the quality control of recovery period plasma collection and patient treatment. To protect the health of blood donors, we must also protect the safety of critically ill and critically ill patients. Up to now, we have a patient cured of more than ten thousand, but also provides an advantage for us to make better use of good rehabilitation plasma treatment of severe and critical illness. I call on patients who are cured and discharged to donate their own plasma, giving hope to critically ill and critically ill patients. Thank you. 2020-02-17 15:52:51
Health News reporter :
Recently, the National Health and Health Commission issued the "Notice of Further Improving the Treatment of Severe and Critical Severe Coronary Pneumonia". At present, everyone attaches great importance to patients with severe and critical illness. What are the current effective treatments? This "Notice" has implications for guiding treatment. 2020-02-17 15:55:24
Wang Guiqiang :
First of all, thank you for your question and thank you for your attention to the introduction of the new Critical and Critical Guidelines. At present, in the treatment of new coronary pneumonia, the treatment of severe and critical illness is the top priority, and it is also the key to reduce the mortality rate.
Since the outbreak of the epidemic, the National Health and Health Commission has sent a national-level expert group, and multidisciplinary experts such as infection, respiratory, and critical care to treat patients with new coronary pneumonia infection on the front line, accumulated a lot of experience in the process. In order to further reduce the case fatality rate and regulate the treatment of critically ill and critically ill patients, experts from the Health and Medical Commission have formulated the specifications for the diagnosis and treatment of critical and critically ill patients. The first is to form a consensus through expert discussions and incorporate some new and feasible methods into the diagnosis and treatment plan. There are several aspects. First, emphasis is placed on supporting symptomatic treatment for critical and critically ill patients, which is basic and critical. Pneumonia is a hypoxemia, so effective oxygen therapy is the most important means. After oxygen therapy or ventilator treatment is used to improve the patient's blood oxygen, the maintenance of the most important organs is vital. In the second aspect, it regulates and refines how to perform oxygen therapy and how to get on the ventilator, so that the grassroots can better implement the oxygen therapy program. In the third aspect, clinical warning indicators were explored for critically ill patients. We know that early intervention is the most critical factor in reducing mortality. In this edition of the guide, early clinical warning indicators are listed for reference by clinicians for early intervention. We emphasize "not treating the disease seriously", and intervening early before the patient gets worse, reducing the mortality rate. The guidelines also added new therapies, including convalescent plasma therapy. The convalescent plasma therapy has achieved results in the treatment of severe and critical illness, so it has also been added to the new edition of the guide. It is hoped that the revised guidelines will guide everyone in the rational and standardized treatment of critically ill and critically ill patients, and further reduce the mortality rate. With the gradual accumulation of experience and the emergence of new therapies, we will also update the guidelines in time to guide everyone's clinical practice. Thank you. 2020-02-17 15:58:56
CCTV reporter :
We just talked about drug development and also mentioned Chinese medicine. We are concerned that many places have used traditional Chinese medicine to treat patients during the epidemic prevention and control stage, including many Chinese medicine doctors who went to Hubei to help. Could you tell us some specifics about the treatment of TCM in this epidemic? Thank you. 2020-02-17 15:59:18
Jiang Jian :
First of all, I would like to thank this reporter for his interest in Chinese medicine. After the outbreak of the new crown pneumonia, the State Administration of Traditional Chinese Medicine, as a member unit of the joint prevention and control mechanism, responded quickly and fully participated. It was the first time to recommend 8 experts , including national medical masters and academicians, to join the national medical treatment expert group. At the same time, some experts from the expert group were sent to Wuhan to understand the condition, diagnose patients, summarize the laws, and guide the dialectical treatment of local Chinese medicine. On this basis, after conscientiously summarizing the clinical treatment experience, while referring to the province's diagnosis and treatment plan and clinical treatment experience, through continuous optimization and adjustment, a TCM treatment plan covering the entire process of the disease has been formed, and it has been included in the joint printing with the National Health and Health Commission Diagnosis and treatment plan. These experts have been fighting on the front line and have been treating patients on the front line.
At the same time, in accordance with the unified deployment, the competent Chinese medicine authorities in various places actively organized the elite forces of Chinese medicine to assist Wuhan. According to statistics, as of now, more than 630 Chinese medical hospitals in 28 provinces (cities, districts) have sent more than 3,100 medical staff to support Hubei. I was sent by the bureau Zhang Boli, Huang Luqi, led a team of experts with Kobayashi three academicians of Chinese medicine and national medical teams in four batches were 588 people to Wuhan, Hubei Province, were settled in Chinese and Western Medicine Hospital, Wuhan Jinyintan hospital, Jiangxia hospital and shelter Raytheon Mountain Hospital launched rescue work. In addition, TCM institutions around the country are also actively participating in the rescue work. TCM experts are involved in the provincial expert groups in all provinces, and 26 provinces (autonomous regions and municipalities) and Xinjiang Production and Construction Corps have separately established provincial-level TCM expert groups. Various places have accumulated a lot of effective treatment methods and experiences in accordance with local conditions in the treatment.
Earlier, the State Council ’s joint prevention and control mechanism issued the “Notice on Establishing and Perfecting a Collaborative Mechanism of Chinese and Western Medicine in the Prevention and Treatment of Infectious Diseases such as New Coronavirus Pneumonia”, requiring localities to establish and improve a collaborative mechanism of traditional Chinese and western medicine, strengthen the system of joint consultation between Chinese and Western medicine, and promote Medicine is deeply involved in the whole process of diagnosis and treatment. As of today, a total of 60,107 confirmed cases of Chinese medicine participated in treatment nationwide , accounting for 85.20% . Among them, the participation of Hubei Traditional Chinese Medicine in the treatment of Hubei Province has been introduced in detail by experts from our bureau at the press conference in Hubei Province. The areas outside Hubei where Traditional Chinese Medicine participated in the treatment of 87 cases were confirmed and discharged .
Next, our bureau will work with the health and health departments to further promote the deepening of the traditional Chinese and western medicine collaboration mechanism, and continue to explore and summarize effective methods for the integration of traditional Chinese and western medicine to maximize the cure rate and reduce the mortality rate. Thank you. 2020-02-17 16:02:01
China Education Television reporter :
A few days ago, medical staff in front said that neocoronary pneumonia is actually a self-limiting disease. Whether we agree with this view, is it the same as the flu, or is it for mild patients to rest at home for a week. Thank you. 2020-02-17 16:05:31
Wang Guiqiang :
First of all, self-limiting disease is an expression common to infectious diseases and some diseases. This expression means that no special intervention is needed, no special etiology treatment is required, and ultimately the patient can heal itself. But self-healing does not mean that no treatment is needed. New crown virus does not require intensive antiviral treatment from a virological perspective. Some patients can effectively eliminate the virus through their relatively strong immunity, and will not become chronic. For the new type of coronavirus infection, some mild patients can be cured through general support for symptomatic treatment and the treatment of clearing and detoxifying traditional Chinese medicine. However, we must emphasize that self-limiting diseases do not mean that they do not require treatment, especially new coronary pneumonia, which is highly contagious. All confirmed cases need to be observed and cared for in medical institutions or institutions such as Wuhan's square cabin. The risk of transmission, on the other hand, to observe the condition to avoid deterioration, the disease progresses suddenly, and indeed a small number of mild cases have progressed suddenly, entering severe, critical, or even life-threatening. Therefore, we emphasize that new crown pneumonia virus infection must be actively treated in hospitals, and do not delay treatment due to its characteristics of self-limiting diseases. I hope that the media will not over-interpret the notion that self-limiting diseases do not require treatment. For new coronary pneumonia, we must emphasize timely diagnosis and treatment at the hospital. Thank you. 2020-02-17 16:10:21
The last two questions. 2020-02-17 16:12:49
Reporter of China Medical Tribune :
Professor Wang Guiqiang mentioned that effective oxygen therapy is an important treatment method for critically ill patients. We saw in the fifth edition of the treatment plan that the respiratory support has been expanded and improved from general oxygen therapy, high-flow oxygen inhalation to noninvasive ventilation. , Invasive ventilation, and salvage treatment, and classification of respiratory support from low to advanced, detailed description of the consideration of this stepwise increase in respiratory support, I would like to ask this hierarchical classification of respiratory support for mild and severe patients has no meaning? 2020-02-17 16:13:21
Wang Guiqiang :
Thank you for asking. First, the new type of coronavirus infection pneumonia affects the lungs. The lungs are an important organ of oxygen exchange. It loses inflammation and blocks oxygen exchange, resulting in hypoxia in the body. Hypoxia can cause a series of organ damage, including important heart, brain, and kidney sensations. Wait for these important organs to become dysfunctional or even fail, leading to the death of the patient. Therefore, oxygen therapy is a vital method. Whether it is a light or severe case, early oxygen therapy can greatly reduce the risk of worsening the condition. In this edition of the guide, different methods are given for different levels of hypoxia. Some are only general oxygen inhalation, some require mask oxygen, some need non-invasive ventilator, and even need invasive ventilator. Therefore, we are stratified according to the severity of the disease and the degree of hypoxia. Mild cases were mentioned just now. The milder cases may be relieved without the need for oxygen therapy and eventually healed. For critically ill patients, systemic and standardized oxygen therapy must be carried out. Only in this way can the disease be further developed.
As mentioned earlier, the specific treatment methods of oxygen therapy are further detailed in the diagnosis and treatment plan for severe and critical illness. The goal is to guide front-line doctors to perform oxygen therapy in a standardized manner, to provide reasonable treatment, and to further reduce the mortality rate through comprehensive treatment. Thank you. 2020-02-17 16:15:11
21st Century Business Herald Reporter :
I just mentioned the square cabin hospital. I understand that patients have already been discharged. I would like to ask what is the discharge standard? What do the rehabilitants need to do in community prevention and control after being discharged from hospital? 2020-02-17 16:18:37
Wang Guiqiang :
The Fangcai Hospital treats mild cases, on the one hand, it solves the problem of isolation of the infection source, and on the other hand, it solves the problem of treating these patients. As mentioned earlier, mild cases may not require special intervention. General supportive treatments can be performed with traditional Chinese medicine for clearing heat and detoxifying. Traditional Chinese medicine is used in the Fangcai Hospital to effectively relieve the patient's condition. All patients in the square cabin hospital are confirmed cases, so the discharge standard is the same as other patients. According to the fifth edition of the guidelines, two negative nucleic acid tests are required to be discharged, and home management is required after discharge, at least two weeks at home. Relative to systematic observation, community-level guidance is also needed. At the same time, it is recommended to return to the hospital for review after two to four weeks. If there is any change in the condition, go to the hospital for treatment. Although the overall recovery of mild cases is very good, but very few may have changes in their condition. We hope that through systematic diagnosis and care, patients can be treated and recovered in a timely manner. Thank you. 2020-02-17 16:19:04
That ’s it for today ’s on-site question and answer, and then please invite Mr. Wang Guiqiang to introduce health knowledge. 2020-02-17 16:19:25
Wang Guiqiang :
There are two issues mentioned by netizens here. One is the issue of recovery plasma that everyone mentioned just now. Netizens mentioned that the recovery period of plasma collected from cured patients is used for the treatment of critically ill patients. Will the plasma be affected when the patient has just recovered and the health is weak?
First, as long as the patient recovers and meets the criteria for discharge isolation, plasma can be collected. Plasma collection is a single plasma collection method. Plasma is taken out and red blood cells, white blood cells, platelets, etc. are returned back. After 200 to 300 ml of this plasma is collected , the patient's plasma completely recovers to its original condition after a week or two. The harm is very small. Don't worry too much. The plasma in the recovery period can treat severe and critically ill patients. I hope that all patients in the recovery period will actively contribute to the plasma and make a contribution to the treatment of severe patients and reduce the mortality rate.
The second question is what is the difference between collecting plasma and donating blood?
The first is that the subjects are different. Only recovery patients who have recovered after infection with neocoronavirus can be used as blood donors. Only such patients have neutralizing antibodies in the plasma, which can effectively treat the infection of neocoronavirus.
The second is to collect only plasma and not whole blood. Generally, blood donation is collected from whole blood, with red blood cells and platelets, and then stratified. In clinical use, either plasma, or platelets, or red blood cells are used for component blood transfusion. This time as long as the plasma, other Give back to the patient.
Third, in addition to routine testing, nucleic acid testing of new coronaviruses should also be performed. Routine tests should be done, such as the detection of infectious disease indicators such as hepatitis B and C to avoid cross infection of blood transfusions. At the same time, the conditional unit needs to detect the antibody of the new crown virus, the higher the neutralizing antibody titer, the better the treatment effect, which is different. Another is to do nucleic acid. To detect viral nucleic acid, it must be negative. Of course, the patients after the cure are all negative, but the test should be performed before blood donation to ensure that there is no new crown virus infection. Others are no different from ordinary blood donation. 2020-02-17 17:04:23
Thank you Mr. Wang Guiqiang for your introduction. We just introduced the relevant knowledge about taking plasma. We have seen that patients who have been continuously discharged from New Coronary Pneumonia have donated plasma voluntarily. Some have not fully recovered and have already made an appointment for registration. We are seeing more recoverers participating in the love relay of plasma donation. The virus is ruthless, and the people are affectionate. Their righteousness is to let love pass, to empower life, and thank the donors for their love. You will bring more hope to more critically ill patients.
Through the introduction of today ’s press conference, we learned that medical staff hangs in pots and put on robes in white, and make white shirts; science and technology workers work hard to fight the night and day, and dare not be late. They are racing against time, racing against the epidemic, fighting viruses, fighting for life. It is precisely because of their efforts that they have given patients powerful help and great confidence that more than 10,000 patients have been cured and discharged. We also look forward to more patients recovering as soon as possible.
Tomorrow we will continue to hold a press conference at the same time. You are welcome to leave your questions to us in advance. You are welcome to continue to pay attention. Today ’s press conference is over. Thank you! 2020-02-17 17:04:45
Publicity Department of the People’s Republic of China. Press conference of the joint prevention and control mechanism of state council on Feb 17, 2020.